[Chronic inflammation and metabolic syndrome in comparison with other signs belonging to the image of polycystic ovary syndrome]

Pol Merkur Lekarski. 2013 Apr;34(202):228-31.
[Article in Polish]

Abstract

Polycystic ovary syndrome (PCOS) is a disorder which concern even 5-10% of women in reproductive age. PCOS is a cause of hyperandrogenism and menstrual disorders with chronic anovulation. The most common clinical symptoms observed in PCOS are hirsutism, acne and obesity. Patients with PCOS often suffer from metabolic disorders like insulin resistance, hyperinsulinemia, dyslipidemia, arteriosclerosis and other abnormalities of the metabolic syndrome. 35 to 60% of women with PCOS are obese and about 50% of them have insulin resistance and hyperinsulinemia. The pathogenesis of atherosclerosis emphasizes the role of inflammatory processes. There are a number of markers of the inflammation process. They are also observed in PCOS and may indicate an increased risk of cardiovascular disease in women. More than 46% of women with PCOS can be diagnosed with metabolic syndrome. Because of the fact that patients with PCOS are at higher risk group of the earlier development of complications such as diabetes t 2, atherosclerosis, hypertension and cardiovascular system diseases, it is important to carry out metabolic disorders diagnosis in every patient with PCOS. It will help to estimate the risk of complications and allow for the implementation of prevention or treatment of metabolic diseases belonging to the image of PCOS.

Publication types

  • Review

MeSH terms

  • Atherosclerosis / diagnosis
  • Diagnosis, Differential
  • Early Diagnosis
  • Female
  • Humans
  • Metabolic Syndrome / diagnosis*
  • Polycystic Ovary Syndrome / diagnosis*
  • Polycystic Ovary Syndrome / prevention & control
  • Risk Factors