Hydrogen peroxide (H2O2) is an important member of the reactive oxygen species, playing various roles in biology and medicine. The conventional detection methods for H2O2 are often restricted by their limited sensitivity, poor selectivity towards H2O2, inappropriate physicochemical properties for detection in biological environments, long response time, etc. We briefly review here some recent nanotechnology--based approaches for H2O2 detection, which present an effective improvement, overcoming some of the limitations of the conventional H2O2 sensing techniques.