Successful endovascular salvage of a pancreatic graft after a venous thrombosis: case report and literature review

Exp Clin Transplant. 2013 Aug;11(4):375-8. doi: 10.6002/ect.2012.0234. Epub 2013 May 29.

Abstract

Simultaneous kidney and pancreatic transplant is the criterion standard for treatment of end-stage renal failure because of diabetic nephropathy. Venous thrombosis occurs in approximately 5% of pancreatic transplants, and it is notoriously difficult to treat, forming the most common nonimmunologic cause of graft loss. We report a case of early detection of pancreatic graft venous thrombosis by measuring urinary amylase, resulting in the successful endovascular salvage of the pancreatic graft.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Amylases / urine
  • Biomarkers / urine
  • Diabetes Mellitus, Type 1 / complications
  • Diabetic Nephropathies / diagnosis
  • Diabetic Nephropathies / etiology
  • Diabetic Nephropathies / surgery*
  • Early Diagnosis
  • Endovascular Procedures*
  • Female
  • Humans
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / etiology
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation
  • Middle Aged
  • Pancreas Transplantation / adverse effects*
  • Phlebography
  • Predictive Value of Tests
  • Radiography, Interventional
  • Thrombectomy / methods*
  • Time Factors
  • Treatment Outcome
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / etiology
  • Venous Thrombosis / therapy*
  • Venous Thrombosis / urine

Substances

  • Biomarkers
  • Amylases