An elevated cibenzoline level interacted with cyclosporine caused ventricular tachyarrhythmia and high defibrillation threshold in hypertrophic cardiomyopathy

Int J Cardiol. 2013 Sep 20;168(1):e24-6. doi: 10.1016/j.ijcard.2013.05.076. Epub 2013 May 29.

Authors

Toshiya Kojima, Yasushi Imai, Katsuhito Fujiu, Kazuo Asada, Jiro Ando, Masafumi Watanabe, Hiroshi Yamashita, Issei Komuro

PMID: 23725817
DOI: 10.1016/j.ijcard.2013.05.076

No abstract available

Keywords: Cibenzoline; Cyclosporine; Drug interaction; High defibrillation threshold; Hypertrophic cardiomyopathy; Ventricular tachycardia.

Publication types

Case Reports
Letter

MeSH terms

Cardiomyopathy, Hypertrophic / blood*
Cardiomyopathy, Hypertrophic / diagnostic imaging
Cardiomyopathy, Hypertrophic / drug therapy
Cyclosporine / adverse effects
Cyclosporine / blood*
Defibrillators, Implantable*
Drug Interactions / physiology
Female
Humans
Imidazoles / adverse effects
Imidazoles / blood*
Middle Aged
Tachycardia, Ventricular / blood*
Tachycardia, Ventricular / chemically induced*
Tachycardia, Ventricular / diagnostic imaging
Ultrasonography

Substances

Imidazoles
Cyclosporine
cifenline