ACE inhibitory peptides derived from aquatic protein

Curr Protein Pept Sci. 2013 May;14(3):235-41. doi: 10.2174/13892037113149990040.

Abstract

Among bioactive peptides derived from aquatic protein, those with ACE inhibitory activity are receiving special attention. This paper presented an overview of ACE inhibitory peptides derived from aquatic proteins, and the peptide sources were listed. The structure-activity relationship and mechanism of action of ACE inhibitory peptides were also discussed. Finally, the antihypertensive effects of ACE inhibitory peptides derived from marine protein, including short-term and long-term influence, were also discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Angiotensin-Converting Enzyme Inhibitors / administration & dosage
  • Angiotensin-Converting Enzyme Inhibitors / chemistry
  • Angiotensin-Converting Enzyme Inhibitors / pharmacology*
  • Animals
  • Aquatic Organisms / chemistry*
  • Humans
  • Peptide Fragments / administration & dosage
  • Peptide Fragments / chemistry
  • Peptide Fragments / pharmacology*
  • Peptidyl-Dipeptidase A / metabolism*
  • Proteins / chemistry*
  • Structure-Activity Relationship

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Peptide Fragments
  • Proteins
  • Peptidyl-Dipeptidase A