Gold(I) triazolyls: organometallic synthesis in air and aqueous media

Chem Commun (Camb). 2013 Jul 7;49(53):5990-2. doi: 10.1039/c3cc43016b.

Abstract

(N-heterocyclic carbene)gold(I) alkynyls and organic azides have undergone cycloadditions in water-t-butanol mixtures with copper metal as the pre-catalyst to give new gold(I) triazolyls in high purity. Substrate tolerability was outlined for organoazides bearing a range of functional groups, and branching alpha to the azide moiety. All products are validated by combustion analysis or high-resolution mass spectrometry; two are also confirmed crystallographically.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Air
  • Alkynes / chemistry
  • Azides / chemistry
  • Coumarins / chemistry
  • Cycloaddition Reaction
  • Gold / chemistry*
  • Organometallic Compounds / chemistry*

Substances

  • Alkynes
  • Azides
  • Coumarins
  • Organometallic Compounds
  • Gold