An insight to chiral monolith for enantioselective nano and micro HPLC: preparation and applications

Robert Healey; Ashraf Ghanem

doi:10.1002/chir.22174

An insight to chiral monolith for enantioselective nano and micro HPLC: preparation and applications

Chirality. 2013 Jun;25(6):314-23. doi: 10.1002/chir.22174.

Authors

Robert Healey¹, Ashraf Ghanem

Affiliation

¹ Chirality Program, Faculty of Applied Science, University of Canberra, Australian Capital Territory (ACT), Australia.

PMID: 23716263
DOI: 10.1002/chir.22174

Abstract

This review gives an overview of chiral separation principles and their application in enantioselective nano/micro high performance liquid chromatography (n/μ-HPLC) using chiral monolith. In particular, developments in silica and polymer chiral monolithic stationary phases are presented. The preparation and applications of chiral monoliths, the basic chiral separation principles and the mechanisms are discussed.

Publication types

Review