Novel heterocyclic thiosemicarbazones derivatives as colorimetric and "turn on" fluorescent sensors for fluoride anion sensing employing hydrogen bonding

Spectrochim Acta A Mol Biomol Spectrosc. 2013 Sep:113:123-9. doi: 10.1016/j.saa.2013.04.103. Epub 2013 May 7.

Abstract

Two novel heterocyclic thiosemicarbazone derivatives have been synthesized, and characterized, by means of spectroscopic and single crystal X-ray diffraction methods. Their chromophoric-fluorogenic response towards anions in competing solvent dimethyl sulfoxide (DMSO) was studied. The receptor shows selective recognition towards fluoride anion. The binding affinity of the receptors with fluoride anion was calculated using UV-visible and fluorescence spectroscopic techniques.

Keywords: Chromophoric and fluorogenic sensor; Deprotonation; Heterocyclic; Single crystal XRD; Thiosemicarbazone; UV–visible spectroscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorption
  • Anions
  • Color
  • Colorimetry / methods*
  • Crystallography, X-Ray
  • Dimethyl Sulfoxide / chemistry
  • Fluorescent Dyes / chemistry*
  • Fluorides / analysis*
  • Heterocyclic Compounds / chemistry*
  • Hydrogen Bonding
  • Molecular Conformation
  • Spectrometry, Fluorescence
  • Spectrophotometry, Ultraviolet
  • Thiosemicarbazones / chemistry*

Substances

  • Anions
  • Fluorescent Dyes
  • Heterocyclic Compounds
  • Thiosemicarbazones
  • Fluorides
  • Dimethyl Sulfoxide