Protein kinase inhibitors: breakthrough medicines and the next generation

Expert Opin Investig Drugs. 2013 Jun;22(6):675-8. doi: 10.1517/13543784.2013.804509.

Abstract

In this issue of Expert Opinion on Investigational Drugs, several protein kinases families and pathways underlying cancer and other diseases are reviewed and several small molecule inhibitors that are in clinical trials are further described. Highlights of these reviews and drug evaluations are summarized in this editorial.

Publication types

  • Editorial
  • Introductory Journal Article

MeSH terms

  • Animals
  • Clinical Trials as Topic
  • Drug Design
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / enzymology
  • Neoplasms / pathology
  • Protein Kinase Inhibitors / pharmacology*
  • Protein Kinases / drug effects*
  • Protein Kinases / metabolism

Substances

  • Protein Kinase Inhibitors
  • Protein Kinases