Water-soluble, membrane-permeable organic fluorescent nanoparticles with large tunability in emission wavelengths and Stokes shifts

Chem Commun (Camb). 2013 Jul 4;49(52):5877-9. doi: 10.1039/c3cc41959b. Epub 2013 May 24.

Abstract

Entrapment within surface-crosslinked micelles (SCMs) enhanced the emission of conventional hydrophobic fluorescent dyes, endowed them with excellent water solubility and membrane permeability, and greatly expanded the Stokes shifts without any covalent structural modification of the dyes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Boron Compounds / chemistry
  • Cell Membrane Permeability
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Hydrophobic and Hydrophilic Interactions
  • Micelles
  • Microscopy, Confocal
  • Nanoparticles / chemistry*
  • Solubility
  • Water / chemistry

Substances

  • 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  • Boron Compounds
  • Fluorescent Dyes
  • Micelles
  • Water