Human immunodeficiency virus-associated lung malignancies

Clin Chest Med. 2013 Jun;34(2):255-72. doi: 10.1016/j.ccm.2013.01.008. Epub 2013 Apr 8.

Abstract

This review of lung malignancies in human immunodeficiency virus (HIV) briefly highlights key epidemiologic and clinical features in the pulmonary involvement of AIDS-defining malignancies of Kaposi sarcoma and non-Hodgkin lymphoma. Then, focusing on non-AIDS defining lung cancer, the epidemiology and mechanisms, clinical presentation, pathology, treatment and outcomes, and prevention of HIV-associated lung cancer are discussed. Finally, the important knowledge gaps and future directions for research related to HIV-associated lung malignancies are highlighted.

Publication types

  • Review

MeSH terms

  • Antiretroviral Therapy, Highly Active*
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • Humans
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / etiology*
  • Lung Neoplasms / prevention & control
  • Lymphoma, AIDS-Related* / epidemiology
  • Lymphoma, AIDS-Related* / therapy
  • Lymphoma, Non-Hodgkin / epidemiology
  • Lymphoma, Non-Hodgkin / therapy
  • Lymphoma, Non-Hodgkin / virology
  • Sarcoma, Kaposi / epidemiology
  • Sarcoma, Kaposi / therapy
  • Sarcoma, Kaposi / virology
  • Smoking / adverse effects