Epidural spinal cord compression in Langerhans cell histiocytosis: a case report

Br J Neurosurg. 2013 Dec;27(6):838-9. doi: 10.3109/02688697.2013.798860. Epub 2013 May 22.

Abstract

Langerhans cell histiocytosis, also known as histiocytosis X, is a rare proliferative disorder of histiocytes. Spinal involvement in the course of Langerhans cell histiocytosis in adult is rare, and epidural location is exceptional. We present a rare case of epidural involvement by Langerhans cell histiocytosis in a 71-year-old man to highlight the importance of considering Langerhans cell histiocytosis in the differential diagnosis of epidural spinal cord compression.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers / analysis
  • Diagnosis, Differential
  • Epidural Space / pathology
  • Epidural Space / surgery*
  • Female
  • Histiocytosis, Langerhans-Cell / pathology
  • Histiocytosis, Langerhans-Cell / surgery*
  • Humans
  • Image Processing, Computer-Assisted
  • Immunohistochemistry
  • Magnetic Resonance Imaging
  • Spinal Cord Compression / etiology*
  • Spinal Cord Compression / pathology
  • Spinal Cord Compression / surgery
  • Spinal Cord Neoplasms / pathology
  • Spinal Cord Neoplasms / surgery*
  • Treatment Outcome

Substances

  • Biomarkers

Supplementary concepts

  • Familial Letterer-Siwe disease