The viability of an integrated coagulation-flocculation and aerobic treatment for purifying wastewater derived from a sauce manufacturing industry was evaluated. The best coagulation-flocculation results were obtained at alkaline pH, showing the greatest turbidity removal efficiency (greater than 90%) and a total chemical oxygen demand (COD) removal of approximately 80%, Additionally, experiments at alkaline pH reduce the reagent requirements (coagulant concentration of 0.4 mL/L and flocculant concentration of 4.0 mL/L) providing a consequent economic benefit as compared to experiments at neutral and acidic pH. Another set of experiments was conducted in a sequencing batch reactor to evaluate the aerobic biodegradability of the remnant dissolved organic matter. The effluent from the physical-chemical pre-treatment at alkaline pH again showed the highest biodegradability (76%), with a global COD total removal of 98%. The results showed that the combination of both techniques could be a viable alternative to efficiently treat wastewater derived from sauce manufacturing.