Abstract
We report the synthesis of a tetrasaccharide with side chain using a light-fluorous-tagged glycosyl donor through the double glycosylation and gradient fluorous solid-phase extraction by adding a little of DCM to improve the solubility for retention for the first time. This convergent method has high efficacy by saving much time and solvent.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Dengue / immunology
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Dengue / prevention & control*
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Dengue Vaccines / chemical synthesis*
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Dengue Virus / drug effects
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Dengue Virus / immunology
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Glycopeptides / chemical synthesis*
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Glycopeptides / chemistry
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Humans
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Oligosaccharides / chemical synthesis*
Substances
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Dengue Vaccines
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Glycopeptides
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Oligosaccharides