An ATP-selective, lanthanide complex luminescent probe

Dalton Trans. 2013 Jul 21;42(27):9840-6. doi: 10.1039/c3dt50986a. Epub 2013 May 20.

Abstract

A luminescent probe based on a europium complex is developed, which effectively distinguishes adenosine-5'-triphosphate (ATP) from adenosine diphosphate (ADP) and adenosine monophosphate (AMP) in pure water at pH 6.8. With a longer lifetime (in ms range), the probe is prospectively applied to biological systems to monitor ATP levels by completely removing the background fluorescence of other molecules.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / analysis*
  • Europium / chemistry*
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Hydrogen-Ion Concentration
  • Luminescence
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry*

Substances

  • Fluorescent Dyes
  • Organometallic Compounds
  • Europium
  • Adenosine Triphosphate