Diabetes mellitus in the next decade: novel pipeline medications to treat hyperglycemia

Clin Ther. 2013 May;35(5):714-23. doi: 10.1016/j.clinthera.2013.04.007.

Abstract

Despite a rapid increase in the number of drugs available to treat hyperglycemia there remain several unmet needs in the prevention and treatment of diabetes. There have also been tremendous advances in our understanding of the pathophysiology of type 2 diabetes, allowing the recognition of novel treatment targets. The purpose of this review is to highlight some of the novel approaches that are being developed to improve glucose control in patients with diabetes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Glucose / drug effects
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Drug Design
  • Humans
  • Hyperglycemia / drug therapy*
  • Hyperglycemia / physiopathology
  • Hypoglycemic Agents / pharmacology
  • Hypoglycemic Agents / therapeutic use*
  • Molecular Targeted Therapy

Substances

  • Blood Glucose
  • Hypoglycemic Agents