The clinical course is described of Salmonella infections in 228 infants. The infection was associated, most frequently, with diarrhoea (with admixture of blood in stools in 57.2% of cases). In infants in the first 3 months of life the course of the disease was more serious, with evidence of toxic organ damage and prolonged diarrhoea. Salmonella infection was often associated with pneumonia or bronchitis (36.8%), urinary tract infection (29.8%), otitis media (22.8%). Iron-deficiency anaemia was present in three-fourths of children. In 35% of the infected children with Salmonella infection decreased level of gamma-globulins was found.