Community-based incidence rate of cardiovascular disease and mortality in 50-75 year old adults

Abstract

Backgrounds and objectives: Updated information on the incidence of the principal cardiovascular diseases (CVD) and cardiovascular mortality is not available in Spain. We have studied the incidence rate of new cases of myocardial infarction, heart failure, stroke and cardiovascular mortality in the adult population in Sanlúcar de Barrameda (Spain).

Material and methods: A community-based prospective follow-up study was conducted. The study enrolled 858 participants aged 50-75 years who were randomly selected from the population and followed-up for 5 years. Age and gender-adjusted incidence rates of cardiovascular disease and cardiovascular mortality were calculated, obtaining complete information for 855 participants. Prognostic risk factors of new cases of cardiovascular disease were obtained using Cox proportional hazard modeling.

Results: The community-based incidence rate of heart failure was 455/100.000 persons-year. The incidence of myocardial infarction, stroke and cardiovascular mortality (506, 216 and 225/100.000 persons-year, respectively) was also very elevated. Male gender, family history of early cardiovascular disease, diabetes, hypertension and sedentary life style were independent risk factors of cardiovascular disease.

Conclusions: The community-based incidence rate of heart failure in Sanlúcar de Barrameda (Spain) is very high, and it is the first to be reported in Spain. The incidence of myocardial infarction is among the highest in Spain.

Keywords: Cardiovascular disease incidence; Cardiovascular mortality; Cardiovascular risk factors; Factores de riesgo cardiovascular; Heart failure; Ictus; Incidencia de enfermedad cardiovascular; Infarto de miocardio; Insuficiencia cardiaca; Mortalidad cardiovascular; Myocardial infarction; Stroke.