Kαλóς και Aγαθóς: how mitochondrial beauty translates into biological virtue

Curr Opin Cell Biol. 2013 Aug;25(4):477-82. doi: 10.1016/j.ceb.2013.03.006. Epub 2013 May 14.

Abstract

We are currently witnessing a stream of major discoveries describing the elementary constituents of complex mitochondrial machineries that define the shape, dynamics and intracellular distribution of the organelle. On the basis of these findings the next wave of research holds the promise of unveiling the so far hidden relationships between the fascinating ultrastructural mitochondrial anatomy and its key roles in many areas of cell biology.

Publication types

  • Review

MeSH terms

  • Animals
  • Calcium Signaling
  • Cell Physiological Phenomena
  • Endoplasmic Reticulum / metabolism
  • Humans
  • Mitochondria / metabolism*
  • Mitochondria / ultrastructure*