Make or break for mitochondria

Catherine L Nezich; Richard J Youle

doi:10.7554/eLife.00804

Make or break for mitochondria

Elife. 2013 May 14:2:e00804. doi: 10.7554/eLife.00804.

Authors

Catherine L Nezich¹, Richard J Youle

Affiliation

¹ is at the Medical Research Council Mitochondrial Biology Unit , Cambridge , United Kingdom and at the National Institute of Neurological Disorders and Stroke , National Institutes of Health , Bethesda , United States nezichc@ninds.nih.gov.

Abstract

Ensuring that mitochondrial DNA is successfully divided between daughter mitochondria involves a complex series of interactions with the endoplasmic reticulum and a variety of enzymes.

Keywords: ERMES; Gem1; Miro; S. cerevisiae; mitochondria; mitochondrial DNA.

Publication types

Comment

MeSH terms

DNA, Fungal / metabolism*
DNA, Mitochondrial / metabolism*
Endoplasmic Reticulum / metabolism*
Mitochondria / metabolism*
Mitochondrial Dynamics*
Saccharomyces cerevisiae / metabolism*

Substances

DNA, Fungal
DNA, Mitochondrial