Two new furostanol saponins from Aspidistra typica

J Asian Nat Prod Res. 2013;15(5):525-31. doi: 10.1080/10286020.2013.787991.

Abstract

Two new furostanol saponins (1 and 2), along with one known saponin (3), were obtained from the rhizomes of Aspidistra typica Baill. Their structures were elucidated as (25R)-26-O-β-d-glucopyranosyl-furost-5-ene-12-one-3β,22α,26-triol-3-O-β-d-glucopyranosyl-(1 → 2)-[β-d-xylopyranosyl-(1 → 3)]-β-d-glucopyranosyl-(1 → 4)-β-d-galactopyranoside (1, typaspidoside A), (25S)-26-O-β-d-glucopyranosyl-furost-5-ene-12-one-3β,22α,26-triol-3-O-β-d-glucopyranosyl-(1 → 2)-[β-d-xylopyranosyl-(1 → 3)]-β-d-glucopyranosyl-(1 → 4)-β-d-galactopyranoside (2, 25S-typaspidoside A), and timosaponin H1 (3), based on the integrative spectroscopic analysis of 1D- and 2D-NMR experiments, ESI-MS data and chemical evidence. The investigation on the chemical components of this plant is reported for the first time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Electron Spin Resonance Spectroscopy
  • Liliaceae / chemistry*
  • Molecular Structure
  • Rhizome / chemistry
  • Saponins / chemistry
  • Saponins / isolation & purification*
  • Stereoisomerism
  • Steroids / chemistry
  • Steroids / isolation & purification*

Substances

  • Drugs, Chinese Herbal
  • Saponins
  • Steroids
  • typaspidoside A