Acceleration of reflex maturation and physical development in suckling rats: effects of a maternal diet containing lipids from goat milk

Nutr Neurosci. 2014 Jan;17(1):1-6. doi: 10.1179/1476830513Y.0000000068. Epub 2013 Nov 26.

Abstract

Objective: To investigate the effects of lipids from goat milk containing conjugated linoleic acids on body weight and reflex ontogeny of neonatal rats treated during the prenatal and suckling periods.

Methods: Three groups were studied: soybean oil (S), coconut oil (C), and goat milk lipids (GM). Reflex maturation (palm grasp, righting reflex, cliff avoidance, vibrissae placing, negative geotaxis, auditory startle, and free-fall righting) as well as body weight evolution were recorded during lactation.

Results: Data demonstrated that the lipids from goat milk accelerated body weight evolution as well as all the reflex maturation investigated (P < 0.05).

Discussion: The supply of goat's milk offered to Wistar rats during pregnancy and lactation provided a variety of fatty acids necessary to accelerate the development of offspring.

Keywords: Conjugated linoleic acid; Development; Goat milk; Rats.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn / embryology
  • Animals, Newborn / growth & development*
  • Animals, Suckling / growth & development
  • Body Weight
  • Brain / drug effects*
  • Brain / embryology
  • Brain / growth & development*
  • Coconut Oil
  • Diet
  • Dietary Fats / administration & dosage*
  • Female
  • Goats
  • Lactation / drug effects
  • Linoleic Acids, Conjugated / administration & dosage
  • Male
  • Maternal Nutritional Physiological Phenomena
  • Milk / chemistry*
  • Plant Oils / administration & dosage
  • Pregnancy
  • Rats
  • Rats, Wistar
  • Soybean Oil / administration & dosage

Substances

  • Dietary Fats
  • Linoleic Acids, Conjugated
  • Plant Oils
  • Soybean Oil
  • Coconut Oil