Characterization of phenolic constituents from ephedra herb extract

Molecules. 2013 May 10;18(5):5326-34. doi: 10.3390/molecules18055326.

Abstract

Nine known compounds: trans-cinnamic acid, catechin, syringin, epicatechin, symplocoside, kaempferol 3-O-rhamnoside 7-O-glucoside, isovitexin 2-O-rhamnoside, herbacetin 7-O-glucoside, and pollenitin B and a new flavonoid glycoside, characterized as herbacetin 7-O-neohesperidoside (1) on the basis of spectroscopic analysis and chemical evidence, were isolated from a traditional crude drug, "Ephedra herb extract". Compound 1 had no effects on HGF-induced motility, whereas herbacetin, which is an aglycone of 1, significantly inhibited it.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzoates* / chemistry
  • Benzoates* / isolation & purification
  • Benzoates* / pharmacology
  • Cell Movement / drug effects*
  • Ephedra / chemistry*
  • Hepatocyte Growth Factor / pharmacology
  • Humans
  • Medicine, Kampo
  • Plant Extracts / chemistry*

Substances

  • Benzoates
  • HGF protein, human
  • Plant Extracts
  • Hepatocyte Growth Factor