An aptamer-gated silica mesoporous material for thrombin detection

Chem Commun (Camb). 2013 Jun 18;49(48):5480-2. doi: 10.1039/c3cc42157k. Epub 2013 May 10.

Abstract

An aptamer-capped mesoporous material for the selective and sensitive detection of α-thrombin in human plasma and serum has been prepared and characterised.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry*
  • Humans
  • Porosity
  • Propylamines
  • Rhodamines / chemistry
  • Silanes / chemistry
  • Silicon Dioxide / chemistry*
  • Spectrometry, Fluorescence*
  • Thrombin / analysis*

Substances

  • Aptamers, Nucleotide
  • Propylamines
  • Rhodamines
  • Silanes
  • Silicon Dioxide
  • Thrombin
  • rhodamine B
  • amino-propyl-triethoxysilane