[Contrast of curative effect and complications between peripheral venous thrombolysis and catheter-direct thrombolysis for acute deep venous thrombosis in lower limbs]

Zhonghua Yi Xue Za Zhi. 2013 Feb 19;93(7):531-3.
[Article in Chinese]

Abstract

Objective: To evaluate the effects of catheter-direct thrombolysis in acute deep venous thrombosis (DVT).

Methods: A total of 86 cases were divided into 2 groups of peripheral venous thrombolysis (group A, n = 33) and catheter-direct thrombolysis (group B, n = 53). The curative effect of two groups was compared by swelling rate and vascular potency.

Results: No significant difference existed in swelling rate between two groups (P > 0.05). Vascular patency rates of group B was significantly better than those of group A (P < 0.01). The incidence of bleeding had no significant difference (P > 0.05) and there was no asymptomatic pulmonary embolism in two groups.

Conclusion: Both treatments of acute DVT are effective in improving symptoms. But catheter-directed thrombolysis results in significant vascular patency rate and does not increase the risk of thrombolytic bleeding.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Catheterization, Peripheral
  • Female
  • Humans
  • Lower Extremity / blood supply
  • Male
  • Middle Aged
  • Thrombolytic Therapy / methods*
  • Treatment Outcome
  • Venous Thrombosis / drug therapy*