ent-Atisane and ent-kaurane diterpenoids from Isodon rosthornii

Rui Zhan; Xiao-Nian Li; Xue Du; Wei-Guang Wang; Ke Dong; Jia Su; Yan Li; Jian-Xin Pu; Han-Dong Sun

doi:10.1016/j.fitote.2013.04.009

ent-Atisane and ent-kaurane diterpenoids from Isodon rosthornii

Fitoterapia. 2013 Jul:88:76-81. doi: 10.1016/j.fitote.2013.04.009. Epub 2013 May 6.

Authors

Rui Zhan¹, Xiao-Nian Li², Xue Du², Wei-Guang Wang¹, Ke Dong², Jia Su², Yan Li², Jian-Xin Pu³, Han-Dong Sun⁴

Affiliations

¹ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China; University of the Chinese Academy of Sciences, Beijing 100039, PR China.
² State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China.
³ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China. Electronic address: pujianxin@mail.kib.ac.cn.
⁴ State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China. Electronic address: hdsun@mail.kib.ac.cn.

PMID: 23660245
DOI: 10.1016/j.fitote.2013.04.009

Abstract

A new ent-atisanoid (1) and three new ent-kauranoids (2-4) belonging to different types, along with four known compounds were isolated from Isodon rosthornii. Their structures were established by means of extensive spectroscopic analysis. The absolute configuration of 1 was further determined by X-ray diffraction. Compounds 1 and 5 are the first example of atisane-type diterpenoid from this plant.

Keywords: Diterpenoids; Isodon rosthornii; Isorosthornins D-G.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diterpenes, Kaurane / chemistry
Diterpenes, Kaurane / isolation & purification*
Isodon / chemistry*
Molecular Structure
Plant Extracts / chemistry*
X-Ray Diffraction

Substances

Diterpenes, Kaurane
Plant Extracts