IGF-1 prevents high glucose-induced cell cycle arrest in cardiomyocytes via β-catenin pathway

Int J Cardiol. 2013 Oct 3;168(3):2869-70. doi: 10.1016/j.ijcard.2013.03.145. Epub 2013 May 1.

Authors

Xi-Yong Yu¹, Yong-Jian Geng, He-Ping Lei, Qiu-Xiong Lin, Jiuhong Yuan, Yangxin Li

Affiliation

¹ Medical Research Center, Guangdong General Hospital, Guangdong Provincial Cardiovascular Institute, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, PR China. Electronic address: yuxycn@hotmail.com.

PMID: 23642823
DOI: 10.1016/j.ijcard.2013.03.145

No abstract available

Keywords: Cell-cycle arrest; IGF-1; Proliferation; siRNA; β-Catenin.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Cycle Checkpoints / drug effects
Cell Cycle Checkpoints / physiology*
Cells, Cultured
Glucose / administration & dosage
Insulin-Like Growth Factor I / physiology*
Myocytes, Cardiac / cytology*
Myocytes, Cardiac / drug effects
Signal Transduction
beta Catenin / physiology*

Substances

beta Catenin
Insulin-Like Growth Factor I
Glucose