Unmasking the role of mast cells in dengue

Elife. 2013 Apr 30:2:e00767. doi: 10.7554/eLife.00767.

Abstract

Immune cells called mast cells can hinder rather than help the body's response to dengue virus, which suggests that mast cell products could be used as biomarkers to identify severe forms of the disease.

Keywords: Human; Mouse; Viruses; chymase; dengue virus; infectious disease; leukotrienes; mast cell; vascular leakage.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dengue / immunology*
  • Humans
  • Mast Cells / immunology*