A new oxyfluorotellurate(IV), indium fluoridopentaoxidotellurate(IV), InTe2O5F, has been synthesized by solid-state reaction and structurally characterized. The crystal structure consists of a three-dimensional framework formed by InO4F2 octahedra and Te2O5 units. The InO4F2 octahedra are linked through the F atoms, which lie on twofold axes, giving rise to helical chains. These helical chains are connected via the Te2O5 units. The helical chains of indium octahedra surround cavities, into which the lone pairs of electrons of the Te atoms point.