Validity of the ages and stages questionnaires in term and preterm infants

Pediatrics. 2013 May;131(5):e1468-74. doi: 10.1542/peds.2012-3313. Epub 2013 Apr 29.

Abstract

Background: This study assessed the concurrent validity of the parent-completed developmental screening measure Ages and Stages Questionnaires, Third Edition (ASQ-3) compared with the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) in children born term, late preterm, or extremely preterm at 8, 18, or 30 months of corrected gestational ages (CGA).

Methods: Data were collected from 306 term and preterm children ages 8, 18, and 30 months' CGA recruited from an ambulatory well-child clinic in Santiago, Chile. Parents completed the ASQ-3 in their homes, and afterward a trained professional administered the Bayley-III in a clinic setting. On the ASQ-3, the presence of any domain screened <2 SDs below the mean area score was considered a positive screen (indicating failure or delay). A Bayley-III score less than ≤1 SD indicated mild or severe delay.

Results: ASQ-3 showed adequate psychometric properties (75% sensitivity and 81% specificity) and modest agreement with the Bayley-III (r = 0.56). Sensitivity, specificity, and correlations between measures improved with testing age and in children who were born extremely preterm.

Conclusions: Considering its psychometric properties, the ASQ-3 can be recommended for routine use in screening low-risk children at 8, 18, and 30 months' CGA and is advisable to be included in follow-up programs for children with biological risk factors such as those born preterm.

Keywords: Ages and Stages Questionnaires; developmental delay; developmental screening; infant; low birth weight; premature.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Age Factors
  • Child Development / physiology*
  • Child, Preschool
  • Databases, Factual
  • Developmental Disabilities / diagnosis*
  • Developmental Disabilities / epidemiology
  • Female
  • Follow-Up Studies
  • Gestational Age
  • Humans
  • Incidence
  • Infant
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature*
  • Male
  • Pregnancy
  • Risk Assessment
  • Surveys and Questionnaires*
  • Term Birth*