Dual infection by streptococcus and atypical mycobacteria following Ahmed glaucoma valve surgery

Semin Ophthalmol. 2013 Jul;28(4):233-5. doi: 10.3109/08820538.2012.760621. Epub 2013 Apr 29.

Abstract

Purpose: To report a case of late postoperative endophthalmitis caused by Streptococcus pneumoniae and conjunctival necrosis by Streptococcus pneumoniae and Mycobacterium fortuitum following Ahmed glaucoma valve (AGV) surgery in a young patient.

Methods: Case report of a 13-year-old boy with purulent exudates and extensive conjunctival necrosis two months following amniotic membrane graft and conjunctival closure (for conjunctival retraction post AGV for secondary glaucoma).

Results: The conjunctiva showed extensive necrosis causing exposure of the tube and plate associated with frank exudates in the area adjoining the plate and anterior chamber mandating explantation of the plate along with intravitreal antibiotics. The vitreous aspirate grew Streptococcus pneumoniae while Streptococcus pneumoniae with Mycobacterium fortuitum was isolated from the explanted plate. Despite adequate control of infection following surgery, the final visual outcome was poor owing to disc pallor.

Conclusion: Conjunctival necrosis and retraction post-AGV can cause late postoperative co-infections by fulminant and slow-growing organisms. A close follow-up is therefore essential in these cases to prevent sight-threatening complications.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Cefazolin / therapeutic use
  • Conjunctiva / pathology
  • Drug Therapy, Combination
  • Endophthalmitis / diagnosis
  • Endophthalmitis / drug therapy
  • Endophthalmitis / microbiology*
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Glaucoma / surgery
  • Glaucoma Drainage Implants*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Mycobacterium Infections, Nontuberculous / diagnosis
  • Mycobacterium Infections, Nontuberculous / drug therapy
  • Mycobacterium Infections, Nontuberculous / microbiology*
  • Mycobacterium fortuitum / drug effects
  • Mycobacterium fortuitum / isolation & purification
  • Necrosis
  • Pneumococcal Infections / diagnosis
  • Pneumococcal Infections / drug therapy
  • Pneumococcal Infections / microbiology*
  • Postoperative Complications*
  • Streptococcus pneumoniae / drug effects
  • Streptococcus pneumoniae / isolation & purification
  • Vitreous Body / surgery

Substances

  • Anti-Bacterial Agents
  • Amikacin
  • Cefazolin