Screening of peptides recognizing simple polycyclic aromatic hydrocarbons

Chem Commun (Camb). 2013 Jun 4;49(44):5088-90. doi: 10.1039/c3cc38907c. Epub 2013 Apr 29.

Abstract

Peptides that specifically bind to the simplest polycyclic aromatic hydrocarbon, naphthalene, were obtained by affinity-based screening using a phage-displayed peptide library. The identified peptide with a β-turn structure showed specific binding to naphthalene present not only on substrates but also in aqueous solutions.

MeSH terms

  • Amino Acid Sequence
  • Naphthalenes / chemistry
  • Naphthalenes / metabolism*
  • Peptide Library
  • Peptides / chemistry
  • Peptides / metabolism*
  • Polycyclic Aromatic Hydrocarbons / chemistry
  • Polycyclic Aromatic Hydrocarbons / metabolism*
  • Protein Binding
  • Protein Structure, Secondary
  • Surface Plasmon Resonance

Substances

  • Naphthalenes
  • Peptide Library
  • Peptides
  • Polycyclic Aromatic Hydrocarbons
  • naphthalene