Fabrication of layer-by-layer assembled biomimetic nanochannels for highly sensitive acetylcholine sensing

Chemistry. 2013 Jun 10;19(24):7686-90. doi: 10.1002/chem.201300528. Epub 2013 Apr 26.

Abstract

Channel tunneling: We have prepared functional biomimetic nanochannels in polyethylene terephthalate (PET) polymer films (see illustration). We used p-sulfonatocalix[4]arene to modify the channel surface by flexible layer-by-layer electrostatic assembly. Using this method we were able to detect acetylcholine with high sensitivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylcholine / analysis*
  • Biomimetics
  • Calixarenes / chemistry
  • Models, Chemical
  • Nanostructures / chemistry*
  • Nanostructures / ultrastructure
  • Polyethylene Terephthalates / chemistry
  • Static Electricity

Substances

  • Polyethylene Terephthalates
  • Calixarenes
  • Acetylcholine