Variability between experts in defining the edge and area of the optic nerve head

Arch Soc Esp Oftalmol. 2013 May;88(5):168-73. doi: 10.1016/j.oftal.2012.07.008. Epub 2012 Oct 9.
[Article in English, Spanish]

Abstract

Objective: Estimation of the error rate in the subjective determination of the optic nerve head edge and area.

Method: 1) 169 images of optic nerve disc were evaluated by five experts for the defining of the edges in 8 positions (every 45°). 2) The estimated areas of 26 cases were compared with the measurements of the Cirrus Optical Coherence Tomography (OCT-Cirrus).

Results: 1) The mean variation of the estimated radius was ±5.2%, with no significant differences between sectors. Specific differences were found between the 5 experts (P <.001), each one compared with the others. 2) The disc area measured by the OCT-Cirros was 1.78 mm² (SD =0.27). The results corresponding to the experts who detected smaller areas were better correlated to the area detected by the OCT-Cirrus (r=0.77-0.88) than the results corresponding to larger areas (r =0.61-0.69) (P <.05 in extreme cases).

Conclusions: There are specific patterns in each expert for defining the disc edges and involve 20% variation in the estimation of the optic nerve area. The experts who detected smaller areas have a higher agreement with the objective method used. A web tool is proposed for self-assessment and training in this task.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Observer Variation
  • Optic Disk / anatomy & histology*
  • Tomography, Optical Coherence / statistics & numerical data