Abstract
It has been found that readily available 3-benzoylacrylic acids undergo palladium-catalyzed decarboxylative arylation with arylboronic acids in the presence of a copper salt oxidant to produce chalcone derivatives. The decarboxylative arylation could also be achieved using aryl halides as the alternative aryl source to expand the applicable scope.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acrylates / chemistry*
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Benzoates / chemistry*
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Catalysis
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Chalcones / chemical synthesis*
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Chalcones / chemistry
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Decarboxylation
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Molecular Structure
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Organometallic Compounds / chemistry*
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Palladium / chemistry*
Substances
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Acrylates
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Benzoates
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Chalcones
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Organometallic Compounds
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benzoylacrylic acid
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Palladium