The effectiveness of current dentin desensitizing agents used to treat dental hypersensitivity: a systematic review

Quintessence Int. 2013 Jul;44(7):535-46. doi: 10.3290/j.qi.a29610.

Abstract

Objective: Dentin desensitizing agents are used in the treatment of dentin hypersensitivity, which is defined as a painful response in the exposed dentin to stimuli that are thermal, evaporative, tactile, osmotic, or chemical. A systematic review was conducted to analyze the clinical effectiveness of current desensitizer with at least 3 months of follow-up.

Method and materials: Eight electronic databases were searched: MedLine (PubMed), Embase, Lilacs, Ibecs, Web of Science, Scopus, Scielo, and The Cochrane Library. Only those clinical trials published from 2000 to 2012 were included.

Results: A total of 3,029 relevant records were identified. After title and abstract examination, 2,645 articles were excluded. A data extraction form was designed and completed by reviewers from the selected studies for a retrospective comparison. From the 99 studies retrieved for detailed review, only 17 had an evaluation time of at least 3-months follow-up and fulfilled the selection criteria.

Conclusion: Cervitec Plus, SE Bond & Protect Liner F, laser, and iontophoresis have shown satisfactory posttreatment results between 3 and 6 months. However, additional clinical trials are warranted to better compare the different types of treatments and their effectiveness in the longer term.

Publication types

  • Evaluation Study
  • Review
  • Systematic Review

MeSH terms

  • Chlorhexidine / therapeutic use
  • Clinical Trials as Topic
  • Dentin Desensitizing Agents / therapeutic use*
  • Dentin Sensitivity / drug therapy*
  • Dentin Sensitivity / etiology
  • Dentin Sensitivity / therapy
  • Dentinal Fluid / physiology*
  • Drug Combinations
  • Follow-Up Studies
  • Gingival Recession / complications
  • Humans
  • Hydrostatic Pressure
  • Iontophoresis
  • Laser Therapy
  • Methacrylates / therapeutic use
  • Resin Cements / therapeutic use
  • Retrospective Studies
  • Thymol / therapeutic use

Substances

  • Dentin Desensitizing Agents
  • Drug Combinations
  • Methacrylates
  • Protect Liner F
  • Resin Cements
  • Sebond
  • chlorhexidine, thymol drug combination
  • Thymol
  • Chlorhexidine