Effectiveness of transoral laser microsurgery for precancerous lesions and early glottic cancer guided by analysis of voice quality

Head Neck. 2014 Jun;36(6):763-7. doi: 10.1002/hed.23368. Epub 2013 Jul 30.

Abstract

Background: The purpose of this study was to show our comparison of the quality of voice obtained after superficial transoral endoscopic cordectomies (types I, II, and III) according to the European Laryngological Society classification versus the more extended cordectomy (types IV and V) among patients with glottic precancerous lesions or early glottic cancer.

Methods: Sixty-two patients underwent vocal assessment after cordectomy (types I-V) for dysplasia, Tis, T1a, T1b, and T2 lesions.

Results: Cordectomy (types I-III) had good vocal outcomes. Cordectomy (types IV-V) showed less favorable outcomes, p < .005 in common parameters of voice range profile and symmetry in stroboscopy after cordectomy (types IV-V), with significant voice handicap index. Recurrences were found in 4 patients with T1b and T2 cancer. Two cases were managed by a higher type of cordectomy, and the other 2 by total laryngectomy.

Conclusion: Effect of transoral laser microsurgery on quality of voice depends on the type of cordectomy and the site of the lesion.

Keywords: cordectomy; glottic cancer; larynx; precancerous lesion; voice analysis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Early Diagnosis
  • Female
  • Glottis / pathology
  • Humans
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / surgery*
  • Laryngectomy*
  • Laryngoscopy* / methods
  • Laser Therapy* / methods
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery*
  • Retrospective Studies
  • Stroboscopy
  • Treatment Outcome
  • Vocal Cords / pathology
  • Voice Quality*