Abstract
Fifteen phenolic compounds, including three caffeoyl derivatives, four gallotannins, three ellagitannins and five flavonoids, were isolated from an 80% MeOH extract of the leaves of Corylopsis coreana Uyeki (Korean winter hazel; CL). The anti-oxidative activities [1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase superoxide scavenging activities (NBT)] and the anti-proliferative activity on human prostate cancer cell lines (DU145 and LNCaP) were also evaluated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic* / chemistry
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Antineoplastic Agents, Phytogenic* / pharmacology
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Antioxidants* / chemistry
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Antioxidants* / pharmacology
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Cell Line, Tumor
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Cell Proliferation / drug effects*
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Drug Screening Assays, Antitumor
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Hamamelidaceae / chemistry*
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Humans
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Male
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Plant Extracts* / chemistry
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Plant Extracts* / pharmacology
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Plant Leaves / chemistry*
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Prostatic Neoplasms / drug therapy*
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Prostatic Neoplasms / metabolism
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Prostatic Neoplasms / pathology
Substances
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Antineoplastic Agents, Phytogenic
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Antioxidants
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Plant Extracts