Induction of molecular remission by using anti-CC-chemokine receptor 4 (anti-CCR4) antibodies for adult T cell leukemia: a risk of opportunistic infection after treatment with anti-CCR4 antibodies

Ann Hematol. 2014 Jan;93(1):169-71. doi: 10.1007/s00277-013-1765-6. Epub 2013 Apr 24.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antibodies, Monoclonal, Humanized / adverse effects
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Antibody-Dependent Cell Cytotoxicity
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Antiviral Agents / therapeutic use
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / adverse effects
  • Cytomegalovirus Infections / drug therapy
  • Cytomegalovirus Infections / etiology*
  • Doxorubicin / administration & dosage
  • Doxorubicin / adverse effects
  • Doxorubicin / analogs & derivatives
  • Encephalitis, Viral / drug therapy
  • Encephalitis, Viral / etiology
  • Female
  • Ganciclovir / therapeutic use
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Leukemia-Lymphoma, Adult T-Cell / drug therapy
  • Leukemia-Lymphoma, Adult T-Cell / therapy*
  • Male
  • Middle Aged
  • Neoplasm Proteins / antagonists & inhibitors*
  • Neoplasm Proteins / immunology
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / etiology*
  • Prednisolone / administration & dosage
  • Prednisolone / adverse effects
  • Receptors, CCR4 / antagonists & inhibitors*
  • Receptors, CCR4 / immunology
  • Remission Induction
  • Stevens-Johnson Syndrome / diagnosis
  • Stevens-Johnson Syndrome / etiology
  • Vincristine / administration & dosage
  • Vincristine / adverse effects

Substances

  • Antibodies, Monoclonal, Humanized
  • Antiviral Agents
  • CCR4 protein, human
  • Immunosuppressive Agents
  • Neoplasm Proteins
  • Receptors, CCR4
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisolone
  • Ganciclovir
  • mogamulizumab

Supplementary concepts

  • VEP-THP protocol