Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients

Nanomedicine (Lond). 2013 Nov;8(11):1807-13. doi: 10.2217/nnm.12.214. Epub 2013 Apr 23.

Abstract

Aim: To gauge patient interest in receiving long-acting injectable nanoformulated antiretroviral therapy.

Methods: Four hundred adult HIV-infected patients currently prescribed antiretroviral therapy were surveyed. χ(2) tests were used for comparisons of interest across groups.

Results: Respondents were 68% male and 53% African-American, with a mean age of 47 years. Overall, 73% of patients indicated that they would definitely or probably try injectable nanoformulated antiretroviral therapy; 61% with weekly dosing; 72% every 2 weekly; and 84% monthly. In total, 48% indicated that they were very concerned about the possible side effects and 35% were very concerned about needle use.

Conclusion: The majority of respondents indicated that they definitely or probably would try parenteral nanoformulated antiretroviral therapy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-HIV Agents / therapeutic use*
  • Female
  • HIV Infections / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Patient Acceptance of Health Care* / statistics & numerical data
  • Young Adult

Substances

  • Anti-HIV Agents