An outbreak of Burkholderia cenocepacia associated with contaminated chlorhexidine solutions prepared in the hospital

Am J Infect Control. 2013 Sep;41(9):e93-6. doi: 10.1016/j.ajic.2013.01.024. Epub 2013 Apr 19.

Abstract

From October to December 2007, an outbreak of Burkholderia cenocepacia occurred in a secondary care hospital. The 19 B cenocepacia isolated from the patients, the chlorhexidine solutions of each different ward, and the purified water that diluted these solutions exhibited an identical pulsed-field gel electrophoresis pattern. Inadequate preparation of chlorhexidine solutions diluted with contaminated purified water may have resulted in an outbreak of B cenocepacia. Adequate preparation of chlorhexidine solutions should be emphasized.

Keywords: Burkholderia cepacia complex; Disinfectants; Hospital outbreak; Water contamination.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Burkholderia Infections / epidemiology*
  • Burkholderia Infections / microbiology
  • Burkholderia cenocepacia / classification
  • Burkholderia cenocepacia / genetics
  • Burkholderia cenocepacia / isolation & purification*
  • Chlorhexidine*
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks*
  • Disinfectants*
  • Drug Contamination*
  • Electrophoresis, Gel, Pulsed-Field
  • Female
  • Genotype
  • Hospitals
  • Humans
  • Male
  • Middle Aged
  • Molecular Typing
  • Secondary Care Centers

Substances

  • Disinfectants
  • Chlorhexidine