Fatal disseminated Scedosporium prolificans infection initiated by ophthalmic involvement in a patient with acute myeloblastic leukemia

Roberto Reinoso; Ester Carreño; Denise Hileeto; Alfredo Corell; J Carlos Pastor; Mónica Cabrero; Lourdes Vázquez; Margarita Calonge

doi:10.1016/j.diagmicrobio.2013.03.006

Fatal disseminated Scedosporium prolificans infection initiated by ophthalmic involvement in a patient with acute myeloblastic leukemia

Diagn Microbiol Infect Dis. 2013 Jul;76(3):375-8. doi: 10.1016/j.diagmicrobio.2013.03.006. Epub 2013 Apr 18.

Authors

Roberto Reinoso¹, Ester Carreño, Denise Hileeto, Alfredo Corell, J Carlos Pastor, Mónica Cabrero, Lourdes Vázquez, Margarita Calonge

Affiliation

¹ Institute for Applied Ophthalmobiology (IOBA), University of Valladolid, 47011 Valladolid, Spain. rreinosot@ioba.med.uva.es

PMID: 23602787
DOI: 10.1016/j.diagmicrobio.2013.03.006

Abstract

Scedosporium prolificans is an opportunistic saprophytic fungus that rapidly disseminates and is intrinsically resistant to currently available antifungal drugs. We report a fatal case of disseminated S. prolificans infection that started with orbital and ocular involvement in a patient with secondary acute myeloblastic leukemia.

Publication types

Case Reports

MeSH terms

Dermatomycoses / diagnosis
Dermatomycoses / drug therapy
Dermatomycoses / microbiology
Eye Infections, Fungal / diagnosis*
Eye Infections, Fungal / drug therapy
Eye Infections, Fungal / microbiology
Fatal Outcome
Female
Fungemia / diagnosis*
Fungemia / drug therapy
Fungemia / microbiology
Humans
Leukemia, Myeloid, Acute / complications*
Leukemia, Myeloid, Acute / drug therapy
Lung Diseases, Fungal / diagnosis
Lung Diseases, Fungal / drug therapy
Lung Diseases, Fungal / microbiology
Molecular Typing
Mycological Typing Techniques
Opportunistic Infections / diagnosis*
Opportunistic Infections / drug therapy
Opportunistic Infections / microbiology
Scedosporium / genetics
Scedosporium / isolation & purification*