Dermatomyositis as the first manifestation of a lung tumor

Rev Port Pneumol. 2013 Jul-Aug;19(4):179-83. doi: 10.1016/j.rppneu.2012.11.002. Epub 2013 Apr 17.
[Article in English, Portuguese]

Abstract

Dermatomyositis (DM) is a rare disease characterised by proximal muscle weakness and a typical cutaneous rash. The muscle biopsy shows inflammatory lesions consistent with myositis, being related to an increased risk of cancer, often considered as a paraneoplastic syndrome. The authors present a case of a 63-year-old man, with progressive proximal muscle weakness and cutaneous rash, appearing in two months. The muscle and skin biopsies were consistent with DM. Chest tomography showed a nodular image in the lingular region and bronchy biopsy confirmed the diagnosis of small cell lung carcinoma (SCLC). This clinical case intends to enhance the importance of a thorough diagnostic study in patients with DM, as it is often a paraneoplastic syndrome.

Keywords: Dermatomiosite; Dermatomyositis; Lung neoplasms; Neoplasias pulmonares; Paraneoplastic syndrome; Síndrome paraneoplásico.

Publication types

  • Case Reports

MeSH terms

  • Dermatomyositis / etiology*
  • Humans
  • Lung Neoplasms / complications*
  • Male
  • Middle Aged
  • Paraneoplastic Syndromes / etiology*
  • Small Cell Lung Carcinoma / complications*