Abstract
Host-pathogen interactions are important for understanding infection mechanism and developing better treatment and prevention of infectious diseases. Many computational studies on host-pathogen interactions have been published. Here, we review recent progress and results in this field and provide a systematic summary, comparison and discussion of computational studies on host-pathogen interactions, including prediction and analysis of host-pathogen protein-protein interactions; basic principles revealed from host-pathogen interactions; and database and software tools for host-pathogen interaction data collection, integration and analysis.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Artificial Intelligence
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Communicable Diseases / etiology
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Computational Biology
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Databases, Protein
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Gene Expression
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Host-Pathogen Interactions* / genetics
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Host-Pathogen Interactions* / physiology
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Human Immunodeficiency Virus Proteins / chemistry
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Human Immunodeficiency Virus Proteins / physiology
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Humans
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Models, Biological
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Protein Interaction Mapping / statistics & numerical data*
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Protozoan Proteins / chemistry
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Protozoan Proteins / physiology
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RNA Interference
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Software
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Structural Homology, Protein
Substances
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Human Immunodeficiency Virus Proteins
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Protozoan Proteins