Age- and gender-specific nomograms for single and dual post-void residual urine in healthy children

Neurourol Urodyn. 2013 Sep;32(7):1014-8. doi: 10.1002/nau.22342. Epub 2013 Apr 17.

Abstract

Purpose: To establish the first age- and gender-specific nomograms for single and two consecutive tests for post-void residual urine (PVR).

Material and methods: Healthy children aged 4-12 years were enrolled for two sets of uroflowmetry and PVR. The first PVR and the lower value of the two consecutive PVRs of each child with a voided volume ≥50 ml were included for construction of Single- and Dual-PVR nomograms. Children with possible urinary tract infection or lower urinary tract dysfunctions were excluded.

Results and limitations: Totally, 1,128 children (583 boys and 545 girls) with a mean age of 7.7 ± 2.2 years were eligible for analysis. The 95th percentile of Single-PVR for all children was 27.2 ml, or 19.2% of bladder capacity (BC), while that for Dual-PVR were 11.2 ml or 6.0% of BC, respectively. Multivariate studies showed that PVR was positively associated with BC, negatively associated with age, higher in boys than girls, and higher in abnormal uroflow patterns. For children aged ≤6 years, a single PVR >30 ml or >21% BC, or repetitive PVR >20 ml or >10% BC can be regarded as elevated. For children aged ≥7 years, a single PVR >20 ml or 15% BC, or repetitive PVR >10 ml or 6% BC can be redefined as elevated.

Conclusions: Age, gender, and BC should be taken into considerations at interpretation of PVR tests in children. Repeating PVR test is recommended when a single PVR is higher than the 95th percentile of age- and gender-specific PVR. Neurourol. Urodynam. 32: 1014-1018, 2013. © 2013 Wiley Periodicals, Inc.

Keywords: children; lower urinary tract dysfunction; nomogram; post-void residual urine; urinary tract infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Multivariate Analysis
  • Nomograms*
  • Predictive Value of Tests
  • Reference Values
  • Reproducibility of Results
  • Sex Factors
  • Urinary Bladder / physiology*
  • Urination*
  • Urodynamics*