Suppression of gene expression by G-quadruplexes in open reading frames depends on G-quadruplex stability

Angew Chem Int Ed Engl. 2013 May 17;52(21):5522-6. doi: 10.1002/anie.201300058. Epub 2013 Apr 15.

Authors

Tamaki Endoh¹, Yu Kawasaki, Naoki Sugimoto

Affiliation

¹ Frontier Institute for Biomolecular Engineering Research, Konan University, 7-1-20 Minatojima-minamimachi, Kobe 650-0047, Japan.

PMID: 23589400
DOI: 10.1002/anie.201300058

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

5' Untranslated Regions / genetics
Cell Culture Techniques
Electrophoresis, Polyacrylamide Gel
Escherichia coli / genetics
G-Quadruplexes*
Gene Expression*
Genes, Reporter
Humans
Luciferases, Firefly / genetics
Luciferases, Renilla / genetics
MCF-7 Cells
Open Reading Frames / genetics*
Optical Imaging
Peptide Chain Elongation, Translational / genetics
Plasmids
Ribosomes / genetics
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Spectrophotometry, Ultraviolet
Thermodynamics

Substances

5' Untranslated Regions
Luciferases, Renilla
Luciferases, Firefly