OptiMAS: a decision support tool for marker-assisted assembly of diverse alleles

J Hered. 2013 Jul-Aug;104(4):586-90. doi: 10.1093/jhered/est020. Epub 2013 Apr 10.

Abstract

Current advances in plant genotyping lead to major progress in the knowledge of genetic architecture of traits of interest. It is increasingly important to develop decision support tools to help breeders and geneticists to conduct marker-assisted selection methods to assemble favorable alleles that are discovered. Algorithms have been implemented, within an interactive graphical interface, to 1) trace parental alleles throughout generations, 2) propose strategies to select the best plants based on estimated molecular scores, and 3) efficiently intermate them depending on the expected value of their progenies. With the possibility to consider a multi-allelic context, OptiMAS opens new prospects to assemble favorable alleles issued from diverse parents and further accelerate genetic gain.

Keywords: QTL; gene pyramiding; marker-assisted selection; multiparental designs; plant breeding.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Alleles*
  • Breeding / methods
  • Chromosome Mapping / methods
  • Decision Support Techniques*
  • Genes, Plant / physiology
  • Genetic Markers / physiology*
  • Genetic Variation*
  • Phenotype
  • Phylogeny
  • Plants / genetics
  • Quantitative Trait Loci / genetics
  • Quantitative Trait Loci / physiology
  • Selection, Genetic / genetics

Substances

  • Genetic Markers