Arylboronic acid chemistry under electrospray conditions

Chemistry. 2013 Jun 3;19(23):7587-94. doi: 10.1002/chem.201204290. Epub 2013 Apr 9.

Abstract

Boronic acids are important in the organic and biological arenas. Thus, their identification and characterization are important. ESI-MS is a well-known tool for such uses. Herein we report a systematic analysis of the chemical behavior of arylboronic acids under ESI-MS conditions. Such information will be very critical to understanding the gas-phase chemistry of boronic acids in an ESI mass spectrometer ion source in general and the MS analysis of boronic acids and their macromolecular conjugates in particular.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boronic Acids / chemistry*
  • Macromolecular Substances / chemistry*
  • Molecular Structure
  • Spectrometry, Mass, Electrospray Ionization / methods*

Substances

  • Boronic Acids
  • Macromolecular Substances