Chronic hepatitis E in HIV patients: rapid progression to cirrhosis and response to oral ribavirin

Clin Infect Dis. 2013 Aug;57(3):465-8. doi: 10.1093/cid/cit224. Epub 2013 Apr 10.

Abstract

Chronic hepatitis E virus infection with rapid progression to cirrhosis is reported in 2 human immunodeficiency virus (HIV)-infected patients with severe immunosuppression. Monotherapy with ribavirin led to temporary viral response and marked improvement of liver damage. Chronic hepatitis E should be regarded as another opportunistic event within HIV infection.

Keywords: HIV; chronic hepatitis E; cirrhosis; immunosuppression; ribavirin.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use*
  • HIV Infections / complications*
  • Hepatitis E / complications*
  • Hepatitis E / drug therapy
  • Hepatitis, Chronic / complications*
  • Hepatitis, Chronic / drug therapy
  • Humans
  • Liver Cirrhosis / pathology*
  • Male
  • Middle Aged
  • Ribavirin / therapeutic use*
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Ribavirin