[Prognostic factors of resected metastatic lung tumor originated from renal cell carcinoma]

Kyobu Geka. 2013 Apr;66(4):275-8.
[Article in Japanese]

Abstract

We performed retrospective analysis of 22 cases who received pulmonary resection of metastases originated from renal cell carcinoma between 1997 and 2011. Patients comprised 18 men and 4 women with a mean age of 63 years (range, 39~79). The total pulmonary resection was 30 times, lobectomy was performed 5 times and wedge resection was 25 times. The 5-year overall survival was 35% and 10-year overall survival was 26%. Prognostic factors were histology of renal cell carcinoma (G1, 2 group vs. G3 group; 2-year survival rate was 69% and 20% respectively, p=0.023) and disease-free interval (less than 24 months vs. more than 24 months; 5-year disease-free survival rate was 22% and 75% respectively, p=0.019) in univariate analysis. Only disease-free interval showed significant difference (p=0.037) in multivariate analysis. This study demonstrated that aggressive surgical resection of pulmonary metastasis from renal cell carcinoma leads to the good prognosis, especially in cases with a long disease-free interval.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Renal Cell / pathology*
  • Female
  • Humans
  • Kidney Neoplasms / pathology*
  • Lung Neoplasms / mortality
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery*
  • Male
  • Metastasectomy
  • Middle Aged
  • Pneumonectomy
  • Prognosis
  • Retrospective Studies